Mit Herz und Wissenschaft für Ihre Herzgesundheit

Prof. Dr. med. André Linka

Facharzt für Allgemeine Innere Medizin und Kardiologie

Ausbildungstellen und klinische Tätigkeit

Ab 07/2024 Praxistätigkeit Cardio Medic Wetzikon
2006 – 2024 Kardiologie als Chefarzt, Kantonsspital Winterthur
2001 – 2006 Kardiologie als Oberarzt, Universitätsspital, Basel
1998 – 2001 Kardiologie als Oberarzt, Universitätsspital Zürich
1996 – 1997 Kardiologie, University of Virginia, Charlottesville, VA, USA
1995 – 1996 Kardiologie, University Hospital of Wales, Cardiff, UK
1992 – 1995 Innere Medizin und Intensivmedizin, Universitätsspital Zürich
1989 – 1992 Kardiologie, Universitätsspital Zürich
1988 – 1989 Innere Medizin, Spital Grenchen
1986 – 1988 Anästhesiologie und operative Intensivmedizin, Kantonsspital Aarau
1985 – 1986 Anästhesiologie, Regionalspital Biel

Habilitation/ Professur

04.11.2009 Titularprofessor, Universität Basel
23.01.2003 Habilitation Medizinische Fakultät Universität Basel:

Dissertation

24.11.1993 Medizinische Fakultät der Universität Zürich

Schulen

1978 – 1985 Medizinstudium Universität Bern, Arztdiplom 19.11.1985
1972 – 1978 Gymnasium in Burgdorf BE
1966 – 1972 Primar- und Sekundarschule in Burgdorf BE

Titel

  • Prof. Dr. med.
  • FESC (Fellow European Society Cardiology)
  • FACC (Fellow American College Cardiology)
  • EHRA Certified Cardiac Device Specialist Level 1 & Level 2 (European Heart Rhythm Association)

Mitgliedschaften

  • Schweizerische Gesellschaft für Innere Medizin 1996
  • Schweizerische Gesellschaft für Kardiologie 1996
  • European Society of Cardiology 1995
  • Member of the American Society of Echocardiography 1998
  • Member of the European Working Group on Echocardiography 1998
  • Erwachsene mit angeborenen Herzfehlern (WATCH) 1999
  • American Heart Association 1999
  • European Society of Cardiology, Fellow (FESC), 2000
  • European Association of Percutaneous Cardiovascular Interventions (EAPCI) 2007
  • Aerzte Gesellschaft des Kantons Zürich, 2007
  • Aerztegesellschaft Winterthur, 2007
  • Arbeitsgruppe Herzschrittmacher und Elektrophysiologie der SGK 2008
  • Arbeitsgruppe interventionelle Kardiologie und akute Koronarsyndrome der SGK 2008
  • Vereiningung Zürcher Internisten, 2008
  • American College of Cardiology, Fellow, 2009
  • Chefärztegesellschaft, Kanton Zürich, 2009
  • European Heart Rhythm Society, 2011

Klinische Tätigkeit

  • Allgemeine Kardiologie, speziell Herzinsuffizienz und koronare Herzerkrankung
  • Arterielle Hypertonie
  • Angeborene Herzfehler im Erwachsenenalter
  • Echokardiographie mit sämtlichen Modalitäten
  • Interventionelle Kardiologie koronar
  • Implantation und Kontrolle von Schrittmachern, inkl. LBBAP, ICD und CRT, sondenlose Schrittmacher (EHRA Devicespezialist Level 1 & 2)

Publikationen (Peer reviewed)

  1. Kerov A, Meier A, Wigger O, Linka A
    CME: Herzinsuffizienz – Überblick, Klinik, Diagnostik und Therapie
    Praxis (Bern 1994). 2022 Apr;111(5):260-269.
  2. Speck Sandro, Bastian Kathleen, Fretz Valentin, Sieber Cornel, Linka André, Kadner Alexander, Fischer Thomas A
    Belastungsdyspnoe und Angina pectoris
    Swiss Med Forum. 2022;22(2122):365-368
  3. Kovacs B, Burri H, Buehler A, Reek S, Sticherling C, Schaer B, Linka A, Ammann P, Müller AS, Dzemali O, Kobza R, Schindler M, Haegeli L, Mayer K, Eriksson U, Herrera-Siklody C, Reichlin T, Steffel J, Saguner AM, Duru F
    High Incidence of Inappropriate Alarms in Patients with Wearable Cardioverter-Defibrillators: Findings from the Swiss WCD Registry
    J Clin Med. 2021 Aug 25;10(17):3811. doi: 10.3390/jcm10173811
  4. Kovacs B, Reek S, Sticherling C, Schaer B, Linka A, Ammann P, Brenner R, Krasniqi N, Müller AS, Dzemali O, Kobza R, Grebmer C, Haegeli L, Berg J, Mayer K, Schläpfer J, Domenichini G, Reichlin T, Roten L, Burri H, Eriksson U, Saguner, AM, Steffel J, Duru F, Swiss Wcd Registry
    Use of the wearable cardioverterdefibrillator – the Swiss experience
    Swiss Med Wkly. 2020 Sep 30;150:w20343
  5. Bombardieri E, Rohrbach M, Greutmann M, Matyas G, Weber R, Radulovic J, Fasnacht Boillat M, Linka A, De Pasquale G, Bonassin F, Attenhofer Jost CH.
    Marfan syndrome and related connective tissue disorders in the current era in Switzerland in 103 patients: medical and surgical management and impact of genetic testing.
    Swiss Med Wkly. 2020;150:w20189
  6. M Taramasso, H Alessandrini, S Kuwata, L Biasco, F Nietlispach, O Gaemperli, M Zuber, A Linka, G Pedrazzini, F Kreidel, C Frerker, K Kuck, F Maisano
    Multicenter Experience With Treatment of Residual Mitral Regurgitation After MitraClip Implantation Using Amplatzer Closure Device: Mid-Term Results
    JACC: Cardivascular Interventions, 2017;10:966-970
  7. Marc S. Sabatine MS, Giugliano RP, Keech AC, et al for the FOURIER Investigators.
    Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.
    N Engl J Med. 2017;376:1713-1722.
  8. Cannon CP, Blazing MA, Giugliano RP, et al. For the IMPROVE-IT Investigators
    Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes.
    N Engl J Med. 2015;372:2387-97.
  9. Bernheim AM, Zuber M, Knechtle B, Linka A, Faeh-Gunz A, De Pasquale G, Seifert B, Pfyffer M, Naegeli B, Attenhofer Jost CH.
    Structural and functional cardiac alterations in Ironman athletes: new insights into athlete’s heart remodeling.
    Int J Cardiol. 2013;164:251-3
  10. Bernheim AM, Attenhofer Jost CH, Zuber M, Pfyffer M, Seifert B, De Pasquale G, Linka A, Faeh-Gunz A, Medeiros-Domingo A, Knechtle B.
    Right ventricle best predicts the race performance in amateur ironman athletes.
    Med Sci Sports Exerc. 2013;45:1593-9
  11. Roe MT, Armstrong PW, Fox KA, on behalf of the TRILOGY ACS Investigators.
    Prasugrel versus clopidogrel for acute coronary syndromes without revascularization.
    N Engl J Med. 2012;367:1297-309
  12. Frielingsdorf J, Fischer TA, Linka A.
    Mitral valve dissection: an unusual case of acute severe mitral regurgitation.
    Eur Heart J. 2012;33:2398
  13. Bernheim AM, Zuber M, Knechtle B, Linka A, Faeh-Gunz A, De Pasquale G, Seifert B, Pfyffer M, Naegeli B, Attenhofer Jost CH.
    Structural and functional cardiac alterations in Ironman athletes: new insights into athlete’s heart remodeling.
    Int J Cardiol. 2013;164:251-3.
  14. Frielingsdorf J, Fischer A, Linka A
    State of the Art 2009: Effiziente Diagnostik der koronaren Herzerkrankung
    Hausarzt Praxis 2009;15:6-10
  15. Fischer TA, Frielingsdorf J, Linka A
    State of the Art 2009: Stabil, instabil, akut – differenzierte Therapie der KHK
    Hausarzt Praxis 2009;15:11-16
  16. Stolz D, Rasch H, Linka A, Di Valentino M, Meyer A, Bögl K, Bruppacher K, Brutsche M, Tamm M.
    A randomized, controlled trial of Bosentan in severe COPD
    Eur Respir J. 2008;32:619-628
  17. Kriemler S, Jansen C, Linka A, Kessel-Schaefer A, Zehnder M, Schürmann T, Kohler M, Bloch K, Brunner-La Rocca H.P.
    Higher pulmonary artery pressure in children than adults upon fast ascent to high altitude.
    Eur Respir J. 2008;32:664-649
  18. Muzzarelli S, Buser P, Bernheim A, Linka A.
    Left ventricular non-compaction: is it really isolated?
    Eur J Echocardiogr. 2008;9:321-2
  19. Aschmann YZ, Kummer O, Linka A, Wenk M, Azzola A, Bodmer M, Krähenbühl S, Haschke M.
    Pharmacokinetics and Pharmacodynamics of Sildenafil in a Patient Treated With Human Immunodeficiency Virus Protease Inhibitors.
    Ther Drug Monit. 2008;30:130-134
  20. Firschke C, Andrassy P, LinkaAZ, Busch R, Martinoff S.
    Adenosine myocardial contrast echo in intermediate severity coronary stenoses: a prospective two-center study
    Int J Cardiovasc Imaging. 2007;23:311-21
  21. Di Valentino M, Friedli BC, Weber S, Linka AZ, Zellweger MJ.
    Acute Left Ventricular Free Wall Rupture During Echocardiography
    J Am Soc Echocardiogr. 2007 Jul 31
  22. Kühne M, Balmelli N, Tobler D, Linka A.
    Isolated cleft of the posterior mitral valve leaflet.
    Int J Cardiol. 2007 Nov 15;122(2):e15.
  23. Conen D, Osswald S, Cron TA, Linka A, Bremerich J, Keller DI, Pfisterer ME, Buser PT
    Value of repeated cardiac magnetic resonance imaging in patients with suspected arrhythmogenic right ventricular cardiomyopathy
    Journal of Cardiovascular Magnetic Resonance. 2006;8:361-366
  24. Ashhkenasi SV, Jansen C, Unser M, Linka A, Osterwalder R, Marsch S, Hunziker P
    Unsupervised image classification of medical ultrasound data by multiresolution elastic registration
    Ultrasound Med Biol. 2006;32:1047-54.
  25. Kessel Schaefer A, Siegemund M, Buser P, Linka A
    Sepsis auf der Intensivstation – Endokarditis als Differentialdiagnose –
    Intensivmedizin und Notfallmedizin; 2006;43:235-240
  26. Kessel Schaefer A, Siegemund M, Buser P, Linka A
    Patientin mit unklarer Sepsis auf der Intensivstation
    Intensivmedizin und Notfallmedizin; 2006;43:78
  27. Bonati LH, Kessel-Schaefer A, Linka AZ, Buser P, Wetzel SG, Radue EW, Lyrer PA, Engelter ST.
    Diffusion-weighted imaging in stroke attributable to patent foramen ovale: significance of concomitant atrial septum aneurysm
    2006;37:2030-4
  28. Kessel-Schaefer A, Linka A, Pretre R, Buser P
    Inferior Sinus Venosus Defect Associated With Incomplete Cor Triatriatum Dexter and Patent Foramen Ovale
    Eur J Echocardiogr. 2006;7:239-242
  29. Pittl, D.I.Keller, C.A.Kaiser, M.Battegay, M.E. Pfisterer, A. Linka
    HAART-Attack bei junger HIV-Patientin
    Internist. 2006;47:939-943
  30. Keller D, Linka A, Buser P, Osswald S.
    Familiäre hypertrophe Kardiomyopathie – eine komplexe, heterogene Erkrankung
    Schweiz Med Forum 2005;5:75–79.
  31. Bernheim A, Ammann P, Sticherling C, Burger P, Schaer B, Brunner-La Rocca HP, Eckstein J, Kiencke S, Kaiser C, Linka A, Buser P, Pfisterer M, Osswald S.
    Right atrial pacing impairs cardiac function during resynchronization therapy: acute effects of DDD pacing compared to VDD pacing.
    J Am Coll Cardiol. 2005;45:1482-7.
  32. Kaiser C, Brunner-La Rocca HP, Buser PT, Bonetti PO, Osswald S, Linka A, Bernheim A, Zutter A, Zellweger M, Grize L, Pfisterer ME; BASKET Investigators
    Incremental cost-effectiveness of drug-eluting stents compared with a third-generation bare-metal stent in a real-world setting: randomised Basel Stent Kosten Effektivitats Trial (BASKET)
    2005;366:921-9.
  33. J Eckstein, W Brett, F Rütter, A Linka
    Acute dyspnea 2 days after chestpain
    2005;91:1468
  34. Derrer F , Gisin S, Linka A, Kindler CH.
    Shone-Anomalie; Fallbericht und Hintergrund.
    2005;54:29-34.
  35. Ramazzina A, Bremerich J, Linka A, Eriksson U
    Asymptomatische Myokarditis nach Infekt der oberen Luftwege
    Dtsch Med Wochenschr. 2005;130:1311-3
  36. Amman P, Kiencke S, Schaer B, Cron TA, Sticherling C, Huldi C, Linka A, Buser P, Pfisterer M, Osswald S.
    Resynchronization in severe heart failure and left bundle branch block: a single center experience
    Swiss Med Wkly. 2004 May 15;134(19-20):277-82.
  37. Burger PC, Linka A, Buser P
    Atriales Piercing
    Kardiovaskuläre Medizin. 2004;7:38-39
  38. Linka A
    Herzkrankheiten und Schwangerschaft.
    In “Kardiologie und Kardiochirurgie. Empfehlungen zur Patienteninformation”. Ed. Buser P, Zerkowski H.-R., Osterhues H.-H., Brett W, Osswald S, Pfisterer M.Steinkopff Verlag Darmstadt, 2003
  39. Widmer A, Linka A, Attenhofer Jost CH, Buergi B, Brunner-La Rocca HP, Salomon F, Seifert B, Jenni R.
    Mechanical Complications after Myocardial Infarction Reliably Predicted using C-Reactive Protein Levels and Lymphocytopenia
    2003;99:25-31.
  40. Bollag L, Attenhofer Jost C, Vogt PR, Linka AZ, Rickli H, Oechslin E, Pretre R, Dubach P, Turina J, Jenni R.
    Symptomatic mechanical heart valve thrombosis: High morbidity and mortality despite successful treatment options
    Swiss Med Wkly. 2001;131:109-115
  41. Linka A, Barton M, Attenhofer Jost C, Jenni.
    Doppler Mirror Image Artifacts in Patients with Mechanical Valve Prosthesis: Implications for the Diagnosis of Mitral Paravalvular Leaks.
    Eur J Echocardiography. 2000;1:138-143
  42. Bianda T, Linka A, Junga G, Brunner H, Steinert H, Kiowski W, Schmid C.
    Prevention of osteoporosis in heart transplant recipients: a comparison of calcitriol with calcitonin and pamidronate.
    Calcif Tissue Int 2000;67:116-121
  43. Prêtre R, Linka A, Jenni R, Turina MI.
    Surgical treatment of acquired left ventricular pseudoaneurysms.
    Ann Thorac Surg 2000:70:553-557.
  44. Jenni R, Kaufmann PA, Jiang Z, Attenhofer C, Linka A, Mandinov A.
    In vitro validation of voulmetric blood flow measurement using Doppler flow wire.
    Ultrasound Med Biol. 2000; 26:1301-1310.
  45. Friedl AC, Attenhofer Jost C, Schalcher C, Amann FW, Flepp M, Jenni R, Linka A, Weber R.
    Acceleration of proven coronary artery disease among HIV-infected patients on potent antiretroviral therapy
    2000;14:2790-2792
  46. Linka A, Jenni R.
    Migration of Intrahepatic Portosystemic Stent into Right Ventricle: An Unusual Cause of Tricuspid Regurgitation
    Circulation 2000;103:161-162
  47. Linka A, Fatio R, Attenhofer Jost
    Double orifice mitral valve
    2000;84:244
  48. Jenni R, Linka A, Barton M.
    Coronary flow reserve assessment by contrast-enhanced second harmonic echo Doppler.
    Letter to the editor. Circulation.2000;101;e100
  49. Firoozan S, Wei K, Linka A, Skyba D, Goodman NC, Kaul S.
    A canine model of chronic ischemic cardiomyopathy: characterization of regional flow-function relations.
    Am J Physiol. 1999;27:H446-H455
  50. Rinaldi CA, Masani ND, Linka AZ, Hall RJH.
    Effect of repetitive episodes of exercise-induced myocardial ischaemia on left ventricular function in patients with chronic stable angina: evidence for cumulative stunning or ischaemic preconditioning?
    1999;81:404-411
  51. Wei K, Jayaweera AR, Firoozan S, Linka A, Skyba D, Kaul S.
    Quantificaton of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion.
    1998;97:473-483
  52. Rinaldi CA, Linka AZ, Masani ND, Avery PG, Jones E, Hall RJC.
    A randomised double blind crossover study to investigate the effects of amlodipine and isosorbide mononitrate on the time course and severity of exercise-induced myocardial stunning.
    1998;98:7749-756
  53. Wei K, Jayaweera AR, Firoozan S, Linka A, , Skyba DM, Kaul S.
    Basis for detection of stenosis using venous administration of microbubble during myocardial contrast echocardiographys: Bolus or continuous infusion?
    J Am Coll Cardiol. 1198;32:252-260
  54. Linka AZ, Sklenar J, Wei K, Jayaweera AR, Skyba DM, Kaul S.
    Assessment of the transmural distribution of myocardial perfusion with contrast echocardiography.
    1998;98:1912-1920
  55. Linka AZ, Skyba DM, Price RJ, Wei K, Skalak TC, Kaul S.
    Spontaneous redistribution after reperfusion. a unique property of AIP 201, an ultrasound contrast agent.
    J Am Coll Cardiol. 1998;32:1765-1772
  56. Sklenar J, Jayaweera AR, Linka AZ, Kaul S.
    Parametric imaging for myocardial contrast echocardiography: pixel-by-pixel incorporation of information from both spatial and temporal domains.
    Computers in Cardiology IEEE. 1998;25: 461-464
  57. Skyba DM, Price RJ, Linka AZ, Skalak TC, Kaul S.
    Direct in vivo visualization of intravascular destruction of microbubbles by ultrasound and its local effects on tissue
    1998;98:290-293
  58. Linka AZ, Ates G, Wei K, Firoozan S, Skyba D, Kaul S.
    Three-dimensional myocardial contrast echocardiography: validation of in-vivo risk and infarct volumes.
    J Am Coll Cardiol. 1997;30:1892-1899
  59. Christ E, Linka A, Junga A, Odermatt M, Steinert H, Kiowski W, Schmid CH.
    Knochendichte und Laborparameter des Knochenstoffwechsels bei Patienten mit terminaler Herzerkrankung.
    Schweiz Med Wochenschr. 1996;126:1553-1559
  60. Christ E, Linka A, Jacky E, Speich R, Marincek B, Schaffner A.
    Sweet’s syndrome involving the musculosceletal system during treatment of promyelocytic leukemia with all-trans retinoid acid.
    1996;10:731-734
  61. Carrel T, Pasic M, Vogt P, von Segesser L, Linka A, Ritter M, Jenni R,Turina M.
    Retrograde ascending aortic dissection: a diagnostic and therapeutic challenge.
    Eur J Cardio-thorac Surg. 1993;7:146-152
  62. Linka A, Ritter M, Turina M, Jenni R.
    Acute tricuspid papillary muscle rupture following blunt chest trauma.
    Am Heart J. 1992;124:799-802
  63. Carrel T, Linka A, Turina M.
    Tricuspid valve obstruction caused by plasmocytoma metastasis.
    Ann Thorac Surg. 1992;54:352-354